Automated cell and tissue culture

 

Robust yet highly-specialized cell culture processes play a key role in almost all areas of modern life sciences. The rapid reproducible supply of cells or tissue samples in high piece numbers is one of the greatest challenges faced by applied biotechnology, pharmaceutics and diagnostics.

Fraunhofer IPA pioneers the field of automated 2D and 3D cell culture. The “Tissue Factory” is the first ever automated high-throughput system that is capable of combining 2D cell cultures with the construction of 3D epidermal skin structures.

Automated cell and tissue culture is more than just the mere combination of biology and automation. In order to successfully transfer a manual cell culture step to a partially or fully-automated process, knowledge of the process and experience in handling cell cultures is essential. Our multidisciplinary team of biology and technology experts has extensive experience in implementing cell culture processes with the use of technical systems. We analyze these processes, adapt them to automated process sequences and develop new key technologies to put them into practice.

Our aim is clear: we want to create an automation solution which enables new protocols to be carried out automatically without having to adapt the cell system to the automated device.

 

 

Single cell handling

Quality rather than quantity: we provide technologies for single cell handling. This enables scientists to research into specific functions of individual cells for diagnostics or new treatment concepts.

 

Cell culture analysis and control technology

Our devices and systems are based on the specific needs of cells, be it dynamic process adjustments or special hardware.

 

Cell and tissue production for screening applications

We develop automation solutions for individual cell systems in drug development and chemical risk assessment. Complex culture systems, stem cells, primary cells and 3D cell cultures call for innovative process sequences, which we then implement according to specific requirements.

 

Cell therapy

Together with our customers, we develop new strategies so that they can realize their manual GMP process as a partially or fully-automated process. In doing so, our primary aim is to consistently cut manufacturing costs by minimizing the infrastructure required.

 

Department brochure “Laboratory Automation and Biomanufacturing Engineering”

 

Product sheet “Automation of cell and tissue cultures”

 

Product sheet “Cell Culture Vessel with integrated sensor electronics”